No modern Indigenous American population has been shown to carry a clear and unambiguous signal of exclusively Ancient Beringian ancestry.

The lineage appears, in the current genetic data, to have either gone extinct, to have been absorbed into other populations through admixture, or to have persisted in forms that are not easily distinguishable from the admixed genetic backgrounds of modern populations.

The most likely explanation, given what the genetic data shows, is admixture — the mixing of the Ancient Beringian lineage with the populations that expanded northward from the south as the climate warmed and human populations grew.

The fossil genetic record from Alaska and adjacent areas from the period after USR1 shows a shift toward the genetic profiles associated with the main Native American branches — a shift that suggests the Ancient Beringian lineage was gradually diluted through mixing with populations moving in from the south.