What the Anzick genome does establish is that whatever came before Clovis, the Clovis people were the ancestors of modern Native Americans.

The Clovis expansion was a founding event for the populations that now inhabit the Americas, even if it was not the very first entry of humans into the hemisphere.

This framing — Clovis as a demographic founding event rather than necessarily the first human presence — is consistent with the most current interpretations of both the genetic and archaeological evidence.

The Americas may have been entered by people somewhat earlier than Clovis, but those earlier people were likely part of the same broad ancestral population, and the Clovis expansion represents a later demographic event that spread a specific technology and perhaps a specific cultural tradition across the continent, becoming the demographic foundation for the diverse Native American populations that followed.

The Clovis Collapse and What Came After