The classic example is the horse and the donkey, which can interbreed to produce mules, but mules are sterile — they cannot themselves reproduce.

This sterility is taken as evidence that horses and donkeys are distinct species with a reproductive barrier that natural selection has built between them.

By this definition — the biological species concept — Neanderthals and Denisovans should perhaps be considered the same species if they could produce fertile offspring together.

Denny herself tells us only that she was born and survived to a significant age; it does not tell us whether she herself was fertile or could reproduce.

But the broader genetic evidence — the presence of Neanderthal DNA in modern human genomes, the presence of Denisovan DNA in modern human genomes — implies that the children of such encounters were fertile and did reproduce, passing the genetic contributions of their ancient-human parents into the modern human gene pool.