The best-documented hypothesis concerns mirabilite specifically.

Mirabilite — sodium sulfate — has well-established medicinal properties.

Taken orally in appropriate quantities, it acts as a laxative; it has been used in traditional medical systems across cultures for exactly this purpose.

Its distinctive salty taste also distinguishes it from gypsum, and it may have served purposes related to food seasoning or preservation.

The Kentucky State Archaeology survey has noted that the cave gypsum could have been used as paint, while mirabilite’s medicinal properties are described as definite — when taken orally, it serves as a laxative.

Its salty taste suggests possible use as a seasoning and as a food preservative.