Against the Odds: The Extraordinary Journey of Manal and Mirhi
When Manal and Mirhi were born, doctors delivered a sobering warning: separation could be nearly impossible, and any attempt carried life-threatening risks. The newborns shared a cranial bone and a complex network of blood vessels, meaning a single misstep could prove fatal. Families and medical teams alike held their breath, praying for a miracle that seemed almost unattainable.
The twins, born in Pakistan with this extremely rare condition, faced a perilous future. Their intertwined skulls and vascular systems made even routine medical interventions fraught with danger. Separation, while potentially life-saving, required unprecedented precision and coordination.

The girls were transferred to Bilkent City Hospital in Ankara, where an international team of surgeons took on the challenge. Drawing on prior successful procedures, the medical team meticulously planned every step. Mixed reality technology allowed them to construct detailed three-dimensional models of the twins’ skulls and brains, enabling surgeons to rehearse the operation virtually before performing it in real life.
The procedure itself was executed in two stages, with the final operation lasting more than 14 hours. Surgeons carefully separated the shared meninges and vascular systems before reconstructing each girl’s cranial bones. Against all odds, the surgery was a success. Within days, both Manal and Mirhi were breathing independently and responding to their surroundings.
Recovery has been remarkable. The twins are now undergoing rehabilitation, gradually learning to sit, move, and explore their world separately. For their parents, holding each daughter individually for the first time was an emotional milestone—a tangible sign of hope realized.
Conclusion
The story of Manal and Mirhi is a testament to the extraordinary capabilities of modern medicine, human resilience, and unwavering hope. What once seemed impossible became possible through expert preparation, advanced technology, and the skilled hands of dedicated surgeons. Today, the twins are embarking on separate lives full of potential, reminding us all that even in the face of overwhelming odds, miracles can and do happen.