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‘Something Borrowed’ Star Colin Egglesfield Opens Up About His Latest Cancer Battle

Colin Egglesfield Faces New Health Battle with Resilience and Hope

Life rarely unfolds the way we expect, and for actor Colin Egglesfield, the journey has been marked by both triumphs and unexpected trials. Known for his charm on screen and his perseverance off of it, the Something Borrowed star has once again been thrust into a deeply personal challenge—one that he has chosen to face with courage and transparency.

Egglesfield, who captured audiences in the 2011 romantic comedy alongside Kate Hudson, John Krasinski, and Ginnifer Goodwin, revealed in a heartfelt Instagram post that he has been diagnosed with prostate cancer. The news comes nearly two decades after he successfully fought through two separate battles with testicular cancer in the early 2000s.

Reflecting on his journey, Colin shared that an interview he gave when he was just 25 still guides him today:

 
 
 
 
 
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A post shared by Colin Egglesfield (@colinegglesfield)

“It’s not about the hand you’re dealt—you can’t control that. What matters is how you play the cards in front of you.”

He admitted that the start of 2025 has been far from easy, but instead of dwelling on fear, he has chosen proactive action. After months of research and consulting medical experts, he opted for surgery, emphasizing that the cancer was caught in its early stages.

“This is another opportunity to decide how I respond to uncertainty,” he said. “I want people to know that they’re never alone in this. Be your own advocate, get your screenings, and don’t be afraid to ask for help.”

Born in Farmington Hills, Michigan, on February 9, 1973, Egglesfield’s path to Hollywood wasn’t linear. With a degree in biology from the University of Iowa, he initially planned on medicine before being discovered by a modeling agency. Campaigns with Versace and Calvin Klein eventually opened the door to acting.

 
 
 
 
 
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A post shared by Colin Egglesfield (@colinegglesfield)

His career highlights include memorable turns as Josh Madden on All My Children, as well as appearances on The Client List, Melrose Place, and Lucifer.

Beyond acting, he authored Agile Artist, a motivational memoir that blends personal stories with lessons on resilience, urging readers to keep pushing toward their dreams. He is also a dedicated philanthropist, supporting cancer awareness efforts and initiatives for youth empowerment.

Conclusion

Colin Egglesfield’s story is not one of defeat but of perseverance. Having already conquered cancer twice before, he now faces this latest diagnosis with the same strength, honesty, and determination that have defined his journey.

His openness is a reminder that illness does not strip away hope—it can, instead, inspire it. In sharing his truth, he encourages others to be vigilant about their health, lean into support systems, and embrace courage in the face of life’s most unpredictable challenges.

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