Just months after celebrating a victory over non-Hodgkin lymphoma, Dave Coulier is now facing another life-altering health battle.
What began as a routine follow-up scan quickly turned into a sobering discovery—one that the beloved Full House star never saw coming.

Coulier, known to millions as the lovable Uncle Joey, had announced in April 2025 that he was officially in remission after being diagnosed with non-Hodgkin lymphoma the previous November.
But during a routine PET scan this past October, doctors found an unexpected spot at the base of his tongue. Additional tests confirmed it was P16 squamous carcinoma, a form of tongue cancer entirely unrelated to his earlier lymphoma diagnosis.
The news was shocking, but Coulier approached it with a calm determination. He explained during a recent appearance on Today that he is currently undergoing an intensive treatment plan—35 rounds of radiation scheduled to conclude by December 31. Despite the challenges ahead, he remains hopeful.
The cure rate for P16 squamous carcinoma is high, and doctors expect a positive outcome. “The prognosis is very good,” he said, emphasizing that early detection once again played a crucial role. His message to the public was simple and heartfelt: stay vigilant. Get your screenings. Pay attention to your health. “It can save your life,” he stressed.
Coulier’s relationship with cancer is deeply personal. He has lost several close family members—his mother, his sister, and his niece Shannon—to breast cancer. His older sister Karen is currently fighting her own cancer battle. Reflecting on the strength he witnessed in the women around him, Coulier said, “If I can be even a fraction as strong as they were, I’ll be okay.”
By speaking openly about his diagnosis, Coulier hopes to turn his experience into something meaningful. His transparency, he says, is meant to encourage others not to wait when it comes to their health. From colonoscopies to breast exams to prostate screenings, he urges people to stay ahead of potential problems before they become serious.
Dave Coulier’s journey is a powerful reminder of how quickly life can shift—and how resilience, optimism, and early detection can make all the difference. After facing two separate cancer diagnoses in less than a year, he continues to meet each challenge with courage and honesty. His determination sends a clear message: taking care of yourself isn’t just important—it’s lifesaving. Our thoughts remain with him and his family as they navigate the road ahead.