The Anzick site has continued to be a reference point for research in the years since the 2014 genome publication, and new analytical approaches continue to contribute additional evidence relevant to the questions the burial raises.

Genomic analysis has advanced significantly since the 2014 study.

The computational methods for analyzing ancient genomes have become more sophisticated, allowing more detailed reconstruction of population history and more precise characterization of genetic relationships.

Subsequent analyses of the Anzick genome, using improved methods and expanded reference databases of modern and ancient genomes from populations around the world, have refined and in some cases modified the conclusions of the original study.

Some subsequent analyses have found that the relationship between the Anzick genome and modern Native American populations is somewhat more complex than the original study suggested — that different Native American populations show different degrees and patterns of relationship to the Anzick genome, reflecting the complex population history of the Americas in the 13,000 years since the child’s death.